|
Key Cell in treatement-resistant Asthma discovered using flow cytometry |
|
Tuesday, 15 May 2012 |
|
ScienceDaily (May 7, 2012) — For
most people with asthma, a couple of puffs from an inhaler filled with
steroids makes breathing easy. But if their lungs become resistant to
the calming effect of that medicine, they live in fear of severe asthma
attacks that could send them to the hospital -- or worse.
Now, new research from the University of Michigan Health System may
help explain what's going on in the lungs of these steroid-resistant
individuals. The findings could aid the development of new treatment
options, and of better ways to identify people at risk of becoming
steroid-resistant.
The U-M scientists have discovered a new type of cell in mice that
appears to be crucial to causing asthma symptoms -- even in the presence
of steroid. The research, published in Nature Medicine, also
showed that people with asthma have a very similar cell type in their
blood at higher levels than people without the condition.
The researchers call the new cell type T2M, for type 2 myeloid --
reflecting its origin in the bone marrow and its involvement in the
"type 2" immune response that causes asthma symptoms. In the lungs, T2M
cells were shown to receive specific distress signals sent out by cells
in the lung lining -- and to produce molecules that lead to more
inflammation.
|
|
Get fresh news at mycyte.org |
|
Tuesday, 01 May 2012 |
image provided by freshprince.wikia.com
|
|
|
Wednesday, 18 April 2012 |
At JISC’s September 2011 Research Integrity Conference, at which BioMed Central presented, there was much support for the seemingly novel concept of setting up a "Data Oscars".
It was one of a number of ideas to better incentivize data sharing (the
problem of, “why should scientists share data if they don’t get any
credit for it?”).
For complete article click HERE
Posted by Iain Hrynaszkiewicz
|
|
|
Flow Cytometry and Lake Health |
|
Wednesday, 11 April 2012 |
|
Scientists in Switzerland have coupled existing technologies to improve the study of freshwaters. By linking flow cytometry, a technology
originally designed for the medical field, and a profiling buoy,
scientists are making new insights into how lakes and ponds change and
respond to environmental pressures.
Flow cytometry is a technique used to count and identify small
samples based on their size and shape. Profiling buoys use a winch to
lower and raise sensors through the water column. Mounting a flow
cytometer on a profiling buoy gives scientists a two-dimensional view of
how chemistry, physics and biology change throughout the water column.
While not common, this technology may soon be available to scientists and lake managers elsewhere to improve drinking water quality and better regulate harmful algal blooms.
Posted Thu Mar 22, 2012 12:17 pm by Kevin Rose
Read More at C&EN
|
|
|
|
<< Start < Prev 1 2 3 4 5 6 7 8 9 10 Next > End >>
|
