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Need a Stem Cell? Just Dust Off an Old B Cell and Reprogram It |
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Monday, 21 April 2008 |
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Fully mature, differentiated B
cells can be reprogrammed to an embryonic-stem-cell-like state, without
the use of an egg, according to a study published in the April 18 issue
of Cell. In previous research, induced
pluripotent stem (IPS) cells typcially have been created from
fibroblasts, a specific type of skin cells that may differentiate into
other types of skin cells. Because there is no way to tell if the
fibroblasts were fully differentiated, the cells used in earlier
experiments may have been less differentiated and therefore easier to
convert to the embryonic-stem-cell-like state of IPS cells.
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Scientists test device to track medication adherence in patients with HIV/AIDS |
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Monday, 21 April 2008 |
Most of us have missed a dose of antibiotic or forgotten to take a
daily vitamin. But when the stakes are higher — as they are for people
with HIV/AIDS — a skipped pill could mean the difference between health
and hazard for the entire population.
Now, a breath monitoring
device developed by scientists at the University of Florida and Xhale
Inc. could help prevent the emergence of drug-resistant strains of HIV
by monitoring medication adherence in high-risk individuals.
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As If Having a Tumor Isn't Enough... |
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Monday, 21 April 2008 |
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New research has shown that the function of a type of cell that
helps modulate immune responses is impaired inside tumors in mice.
Researchers also identified several factors that may contribute
to an accumulation of these cells, called T regulatory cells (Tregs),
within and around the tumor, which may be how they respond to their
loss of functionality. The study, by scientists at the National
Cancer Institute (NCI), part of the National Institutes of Health,
appeared online April 18, 2008, in The Journal of Immunology.
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Stem Cells And Cancer: Scientists Investigate A Fine Balancing Act |
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Monday, 14 April 2008 |
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Speaking at the UK National Stem Cell Network Annual Science Meeting in
Edinburgh, on April 11, Professor Silvia Marino shows how the
mechanisms normally involved in balancing different functions of stem
cells may also contribute to cancer. Her team from Barts and the London
School of Medicine and Dentistry is currently delving into these
mechanisms to understand how stem cells are normally regulated and what
role they may play in malignant brain tumours.
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