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Need a Stem Cell? Just Dust Off an Old B Cell and Reprogram It
Monday, 21 April 2008
Fully mature, differentiated B cells can be reprogrammed to an embryonic-stem-cell-like state, without the use of an egg, according to a study published in the April 18 issue of Cell. In previous research, induced pluripotent stem (IPS) cells typcially have been created from fibroblasts, a specific type of skin cells that may differentiate into other types of skin cells. Because there is no way to tell if the fibroblasts were fully differentiated, the cells used in earlier experiments may have been less differentiated and therefore easier to convert to the embryonic-stem-cell-like state of IPS cells.
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Scientists test device to track medication adherence in patients with HIV/AIDS
Monday, 21 April 2008
Most of us have missed a dose of antibiotic or forgotten to take a daily vitamin. But when the stakes are higher — as they are for people with HIV/AIDS — a skipped pill could mean the difference between health and hazard for the entire population.
Now, a breath monitoring device developed by scientists at the University of Florida and Xhale Inc. could help prevent the emergence of drug-resistant strains of HIV by monitoring medication adherence in high-risk individuals.
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As If Having a Tumor Isn't Enough...
Monday, 21 April 2008

New research has shown that the function of a type of cell that helps modulate immune responses is impaired inside tumors in mice. Researchers also identified several factors that may contribute to an accumulation of these cells, called T regulatory cells (Tregs), within and around the tumor, which may be how they respond to their loss of functionality. The study, by scientists at the National Cancer Institute (NCI), part of the National Institutes of Health, appeared online April 18, 2008, in The Journal of Immunology.

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Stem Cells And Cancer: Scientists Investigate A Fine Balancing Act
Monday, 14 April 2008

Speaking at the UK National Stem Cell Network Annual Science Meeting in Edinburgh, on April 11, Professor Silvia Marino shows how the mechanisms normally involved in balancing different functions of stem cells may also contribute to cancer. Her team from Barts and the London School of Medicine and Dentistry is currently delving into these mechanisms to understand how stem cells are normally regulated and what role they may play in malignant brain tumours.

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