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Progress on the Analytical Cytometry Standard (ACS) by John Quinn Ph.D |
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Thursday, 24 July 2008 |
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MIFlowCyt, the minimum information required for reporting a flow cytometric experiment, was accepted in March of this year by ISAC as the standard detailing what information the Analytical Cytometry Standard (ACS) should contain, but specifies nothing regarding the format of the newest data file standard (Unfamiliar with the ACS? View my previous post here ). The discussion within our community has now turned to what that format will be. At the ISAC meeting in Budapest, the Data Standards Task Force (DSTF) hosted several discussions and assembled the attending members for a meeting in an attempt to gauge the prevailing opinions on what the format needs to be for ACS. The conclusion was that the ACS file itself should be a container file, meaning that it stores a number of other data containing files that can be of a variety of formats. The task force agreed that this was the best way to capture a large amount of metadata while recording the actual measurements in a format that could lack most header information and thus be read by a wide array of non-proprietary software.
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Rare Mutant Cells Glimpsed: Imaging System May Help Understand Origins Of Cancer |
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Wednesday, 23 July 2008 |
MIT biological engineers have developed a new imaging
system that allows them to see cells that have undergone a specific
mutation. The work, which could help scientists understand how precancerous
mutations arise, marks the first time researchers have been able to
pinpoint the number and location of mutant cells--cells with a
particular mutation--in intact tissue. In this case, the researchers
worked with mouse pancreatic cells.
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NIST trumps the clumps: Making biologic drugs safer |
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Wednesday, 23 July 2008 |
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Scientists at the National Institute of Standards and Technology
(NIST) have developed a technique to measure the formation of clumps of
proteins in protein-based pharmaceuticals. This first systematic study*
clarifies the conditions under which scientists can be assured that
their instruments are faithfully measuring the formation of protein
aggregates, a major concern because of its impact on quality control
and safety in biologic drug manufacturing.
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FloCyte Regionals: A Gateway to the World of Flow |
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Monday, 21 July 2008 |
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Sunny Davis, California was the site of the latest FloCyte Regional Intensive Short Course in Flow Cytometry. This course is designed to provide the background, theory and hands-on training necessary to put scientists from all walks in the driver's seat of their own flow experiements. These courses are ongoing and may be in your area soon. If you are thinking about signing up, and want a user's perspective of a week in the life of a FloCyte attendee, then read more...
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