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Background.Flow cytometry (FC) is considered a sensitive and specific technique for the detection of occult lymphoma cells in cerebrospinal fluid.Methods.The diagnostic sensitivity of a FC...
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Background:Therapeutic drug monitoring (TDM) of immunosuppressive drugs after organ transplantation is based on measuring blood levels alone, which often results in under‐ or over‐immunosuppression. Previous...
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Background.The final response that leads to basophil degranulation results from a cross‐talk between activatory and inhibitory signals. However, in the context of basophil biology, the...
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Background:In patients with chronic lymphocytic leukemia (CLL), aberrant expression of the T‐lineage antigen CD8 was reported in low frequencies. The clinical impact of this phenomenon...
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Basophils are key effector cells in allergic inflammatory reactions. However, the mechanisms of FcεRI‐induced degranulation are complex and remain to be disentangled. Signal transducer and...
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Background:CD80 is a member of the B7 family of immune coregulatory proteins that mediate both immune activation and suppression. CD80 in particular has recently been...
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Background:Differential cell count in bronchoalveolar lavage (BAL) has an important role in the diagnosis of pulmonary diseases. Optical microscopy method is usually chosen to identify...
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Aims and objectives:To build an artificial neural network (ANN) model for the detection of carcinoma in effusion cytology.Materials and methods:We selected a total of 114...
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Introduction:Expression of ZAP‐70 by chronic lymphocytic leukemia (CLL) is associated with more aggressive disease and can help differentiate CLL using mutated immunoglobulin heavy chain variable...
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Background:Flow cytometric immunophenotyping has an established role in the diagnosis and monitoring of B‐lymphoblastic leukemia (B‐LL). However, the search continues for an optimal reagent set...
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Introduction:Zeta‐chain‐associated protein kinase 70 (ZAP‐70) has been identified as an independent prognostic marker in chronic lymphocytic leukemia (CLL). Based on our previous studies, we have...
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Background:The aim of clinical laboratories is to produce accurate and reproducible results to enable effective and reliable clinical practice and patient management. The standard approach...
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A proposal for a scoring system in the diagnosis of chronic lymphoproliferative diseases other than CLL has been recently published in Cytometry Part B. The...
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Background:Stable flow cytometric markers for malignant myeloid cells are highly warranted. Based on data from stem cell research, we hypothesized that the human inhibitory C‐type...
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Background:Flow cytometric CD34+ stem cell enumeration is routinely performed to optimize timing of peripheral blood stem cell collections and assess engraftment capability of the apheresis...
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Background:Detection of basal levels of CD34 progenitor cells is a rare event analysis enumerating cells down to 1 cell/μl. A reproducible analytic approach was used...
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Background:Immunoglobulins (IVIG) have been shown to be useful in adults suffering from sepsis. In contrast, prophylactic and curative IVIG trials failed to show beneficial effects...
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Background:Although the impairment of HIV‐specific T lymphocytes is evident during chronic HIV‐infection, it is unclear whether the increased CD8+ T cells associates with either selective...
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Background:HIV‐1 infection is associated with depletion of naïve T cell subsets and skewed T cell differentiation and maturation, leading to accumulation of T cells at...
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Background:Regulatory T cells (Tregs) modulate the host response in infectious diseases and are key mediators of peripheral tolerance. Cryopreservation of peripheral blood mononuclear cells (PBMCs)...
Cytometry Part B Abstracts 
