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Tuesday, 12 August 2008
A new development in multiphoton microscopy, members of the Peter Saggau laboratory at Baylor College of Medicine in Houston have developed the first multiphoton microscope that can capture 3-D images of a calcium wave in a single neuron.

In experiments detailed in the June 2008 issue of Nature Neuroscience, the researchers performed structural and functional imaging of neurons in rat brain slices, rapidly scanning many user-selected sites on dendrites.

Read more here .

 
B Cells Can Act Alone in Autoimmune Disease
Tuesday, 12 August 2008
B cells, the source of damaging autoantibodies, have long been thought to depend upon T cells for their activation and were not considered important in the initiation of autoimmune diseases like lupus or rheumatoid arthritis.
In the Aug. 7 online issue of the journal of Immunity, Yale University researchers turn this paradigm on its head by showing that in systemic autoimmune diseases B cells can be activated the absence of T cells.
Read more...
 
Stem Cell Sites and Summits
Friday, 08 August 2008
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My PI recently asked me to go to stemcellresources.org, check it out and report back on the goods. I am happy to report that stemcellresources.org, aside from being easily navigable and well organized, contains networking opportunites, multimedia presentations (I like the podcasts, personally) and links to established resources and information in a field that continues to shape the way we humans think of health and disease.
Read more...
 
Modeling the Speed at which HIV Escapes the Immune Response
Thursday, 31 July 2008

A novel computational model made by scientists in The Netherlands illustrates how HIV evades the immune system. Utrecht University researchers say that their study focuses on detailed interactions between a mutating virus and the immune system.  A research article in the open-access journal PLoS Computational Biology highlights the fact that HIV relies upon viral variants called “escape mutants” to avoid being recognised by the human immune system.

Read more...
 
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